Research from Washington University in St. Louis has identified variations in brain scans that they believe identify portions of the brain that are responsible for intelligence.
As suspected (and as explained by cartoons) brain size does play a small role; they said that brain size accounts for 6.7 percent of variance in intelligence. Recent research has placed the brain’s prefrontal cortex, a region just behind the forehead, as providing for 5 percent of the variation in intelligence between people.
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