Alpine ibex taking a chimney-top break in the French Alps, 2019 - by Sandro Lovari, Italian

The organizer for Walaa's GoFundMe wanted to share this video here as well - please if you are able to help Walaa and her family escape Gaza during this genocide, I will leave the donation link below. Share with your family, your friends, and your followers - time is running out.

Me Giving a Pressed Conference: our advocacy for the disabled must include the addict, the imperfect victim, those we despise; the right to autonomy and life cannot devolve into a popularity contest

Reporter I Hate (Not Sexual Tension): Does that include all the attendees of the Bored Ape NFT event who went blind

Me: *Blood streaming from my nostrils and eyes* david, it includes everyone

"ne'er-do-well" is such a harsh criticism like bro ne'er? e'er? like youd think at least some'imes id do well but nope. ne'er

I know I don't shut up about this but frankly not enough people are angry about the 5-day/40 hour workweek (and I am AWARE a lot of people work even more than that). I feel like a lot more people should be absolutely furious that we only really have two days a week and some occasional hours in the evening to socialise, run errands, do chores, or relax.

It's no wonder so many people are profoundly lonely and disconnected from their communities when maintaining a social life in what little free time we have is incredibly difficult. If you have kids, a second job, a very long commute, or other responsibilities, it's nearly impossible.

We literally aren't meant to live like this and I'll never stop being shocked how many people just take it as the natural state of things and don't want to throw a brick through a billionaire's window every time they think of it.

you call this place "wall greens" yet its walls... are not green? how very pecuilar...

ah i see now. so "walgreen" was a clan of bandits who conquered various, smaller apothecaries in order to acquire the vast empire they now sit upon. how very cruel, this "america". you are ruled by warlords and do nothing to usurp them?

Crochet Your Next Big Catch with Free Patterns from the National Park Service

official fish post

I'm so extremely serious when I say doctors should be put through an extremely extensive reliscensing process every 10 years. Doctors should have their knowledge scrutinized against current medical research and be de-barred at even the tiniest discrepancy. Too many old doctors absolutely refuse to stay up to date on research and dismiss patients because of their personal experiences. Too many people die every year because doctors don't take us seriously and refuse to listen to people who KNOW something is wrong. Too many people are told their problems are nothing and come back in a year or more with serious illnesses and doctors are just like "lol everyone makes mistakes" but doctors mistakes routinely cost people their lives! I'm tired of medical malpractice being swept away under the guise of "mistakes were made."

If lawyers have to take 20-30 hours of continuing law education classes every single year, doctors should have to go through a reliscencing process every 10.

First, to get ahead of it, the vast majority of doctors do need "continuing education" credits of some sort or another. It varies heavily from place to place. But the real hurdle here is that a) we don't actually have enough doctors and b) they don't have enough time or focus to keep up with everything. So I'd gently suggest, rather than piling "re-attend med school every decade or lose your livelihood" on top of the doctors, we:

Imagine a world where there were a dozen other doctors--well-rested doctors who have time to keep up on the latest research, even!--you could go see if yours was shitty. And as a bonus, imagine that was paid for by taxes and wouldn't bankrupt you.

Crazy, right?

Jane Crowther

Guys, stop being crap to creators. You aren’t hurting Amazon. You’re stealing from writers.

This is an extremely frustrating trend to watch happen. Indie writers already work so hard, and there's nothing they can do. Amazon doesn't give a damn, they profit either way.

Please download Libby if you want access to free ebooks that were legitimately purchased by a library. Hurting people like this means they can't afford to write books.

Full Transcript at the link; 3-minute listen.

Quote:

By taking biopsies from long COVID patients before and after exercising, scientists in the Netherlands constructed a startling picture of widespread abnormalities in muscle tissue that may explain this severe reaction to physical activity.

Among the most striking findings were clear signs that the cellular power plants, the mitochondria, are compromised and the tissue starved for energy.

"We saw this immediately and it's very profound," says Braeden Charlton, one of the study's authors at Vrije University in Amsterdam.

The tissue samples from long COVID patients also revealed severe muscle damage, a disturbed immune response, and a buildup of microclots.

"This is a very real disease," says Charlton. "We see this at basically every parameter that we measure."

I feel insane seeing stuff like this because this research already exists for Myalgic Encephalomyelitis, a post viral condition caused by multiple types of viral infections that a LOT of people with "Long Covid" meet the diagnostic criteria for.

This article mentions that ME/CFS is a "similar complex condition" but that's DEEPLY underreporting the similarities. The phrase "post exertional malaise" (now researchers are trying to replace it but this article uses that phrase) was INVENTED for ME/CFS. It's the only known condition, before "long covid", that causes these kinds of symptoms after exertion!

It's good to know for sure that it's the same mechanisms at play when the inciting viral infection is Covid and not, for instance, Epstein-Barr or RSV, but half the time it doesn't seem like researchers are making comparisons at all, just reinventing the wheel and acting like "long covid" is a totally new phenomenon with no previous point of comparison. There are literally drugs in human trials to try to treat the mitochondrial dysfunction in ME, this dysfunction is well-established and fairly well understood and I feel insane when ppl report on long covid without mentioning that there is already a named and studied condition that accounts for this subset of symptoms!!

SOME researchers are drawing comparisons but they're largely ME researchers who everyone else is largely cignoring because of the widespread perception that ME is a fake disease for lazy women.

That same perception btw is why "graded exercise therapy" (GET), or exercise gradually increasing in intensity, cwas for years the go-to treatment despite MOUNTAINS of evidence that it makes ME patients sicker. Some end up permanently bedbound and unable to even eat or drink without a feeding tube/IV because the damage is so bad! The GET recommendation was finally changed only in the past few years in the US and the UK, and many doctors hate that they're not allowed to recommend it anymore, because they insist despite the evidence that ME/CFS is psychological and ME patients are just "deconditioned" and too lazy to do anything about it.

Now the same kind of "treatment" is being recommended for long covid patients despite evidence showing exercise is having the same kinds of cellular effects as it does in ME patients. "Taking PEM into account" sounds gentler but I'm deeply concerned about the reinvention of GET for patients who meet all the criteria for an illness that's been shown definitively to become permanently worse with GET. This mitochondrial damage is progressive in ME, and there's no reason to believe patients who meet all the criteria of ME after Covid won't experience the same progression if they force themselves past their energy envelope in such a systematic way.

PEM happens in part (it's complex) because your anaerobic threshold gets dramatically reduced with this mitochondrial damage. Every time you hit that anaerobic threshold, you're injuring your cells more and more. It's deeply worrying that GET is being recommended for long covid patients who meet the criteria for ME when research like this study keeps showing it's the same phenomenon.